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Cinnamon is one of the most popular spices in different countries and cultures. Cinnamon spices sold in stores may be a combination of cinnamon varieties. The most common type of cinnamon sold in North America is Cassia cinnamon, made from evergreen tree bark in Southeast Asia. Another type is Cinnamomum verum or Ceylon cinnamon.


Public use of cinnamon

Cinnamon (Cassia) is used orally for diabetes, pre-diabetes, flatulence, muscle spasms and digestive tract, to prevent nausea and vomiting, diarrhea, infection, colds and loss of appetite. It is also used for impotence, inflammation and joint pain, testicular hernia, menopausal symptoms, amenorrhea (abstinence), as a cause of abortion, for angina, renal disorders, hypertension, and cancer.
Cassia cinnamon is topically applied as an anti-mosquito. Cassia cinnamon is used in the food industry as a flavoring agent.

Food safety

It is likely to be harmless when used orally in normal amounts. Cinnamon cassia has been known to be safe in four-month clinical trials. Cinnamon generally falls into the harmless group in the United States (GRAS).
Topical use for the short term is probably harmless. Cinnamon Oil has been used topically in a clinical trial.
It should be noted that using cinnamon orally in high doses for a long time can have disadvantages. Some cassia cinnamon products contain high amounts of Coumarin which can lead to hepatotoxicity, which can be resolved after the coumarin is discontinued. In most cases, taking Cassia cinnamon will not have enough Coumarin to cause hepatotoxicity; however, in highly sensitive individuals such as those with liver disease, long-term consumption and high doses of Cassia cinnamon may exacerbate this condition, and it should be used with caution.

Use in children: If used orally in normal amounts, it may be harmless. Oral consumption of Cinnamon cinnamon at 1g/day has been reported harmless for adolescents aged 13 to 18 for three months.
Use during pregnancy and lactation: There is no detailed information and studies on the safety of Casia cinnamon provided that it is used in medicinal products during pregnancy and lactation. Drug use during this period should be avoided.


Effectiveness in clinical trials

Several clinical studies have been conducted on cinnamon Cassia and type II diabetes mellitus, some of which have had significant effects. Analysis of results of 543 clinical trials in adults with type 2 diabetes show that consuming 120mg to 6g of Cassia cinnamon daily for 4 to 18 weeks reduces fasting blood glucose by 25mg/dL, total cholesterol was reduced by 16mg/dL, LDL cholesterol was 9mg/dL and triglycerides decreased by 30mg/dL. Also, the level of useful cholesterol (HDL) increased by 2mg/dl. Despite a decrease in fasting blood sugar with cassia cinnamon, its effect on glycosylated hemoglobin (HbA1C) was not significant. Clinical trials show that daily consumption of cinnamon in patients with insulin-dependent diabetes mellitus (Type I) did not affect fasting blood glucose, HbA1C, insulin sensitivity, or reduced rates of hypoglycemia.

Side effects

Cassia cinnamon seems to be well tolerated for most people and in most cases no significant side effects have been reported. However, in rare cases cinnamon may cause itching or skin allergic reactions when taken orally or topically. A case of hypoglycemia has also been reported for a patient with cinnamon abuse, which does not indicate that consumption of Cassia cinnamon caused this seizure. Although there is concern about the use of Cassia cinnamon due to the content of Coumarin and as a result of the possibility of liver damage. However, most studies show that the amount of Coumarin present in cinnamon is very low for causing side effects in most patients.

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